About

The VACSTM Technology and Founding of Cellular Highways

Cellular Highways was founded to take fluorescence-based cell sorting into new medical and research applications, requiring fast, gentle, sterile, scalable cell sorting, using the unique potential of the VACS technology. Cellular Highways is a spin-out from TTP plc, based in Melbourn Science Park, Cambridgeshire, UK.

Timeline

2016

Our project began within the Life Science department at TTP plc, which had worked on cell sorting problems for several years, applying a range of droplet-handling microdevices to life science instrumentation. We saw the huge potential high-throughput fully-enclosed cell sorting within cell therapy, and the enormous technology challenge to make this a reality.

2016

2017

The idea of VACS was born. Most of the year was spent in the lab, making and testing successive generations of the microfluidic chip that implements this idea, and improving our instrumentation.

2017

2018

First results on human blood samples, with collaborators at GSK (now published in Lab on a Chip). We also got our first feasibility results with a prominent cell therapy partner, showing at, an experimental scale, that the VACS technology was capable of sorting cells in a CART manufacturing process, without loss of cell viability or functionality.

2018

2019

Cellular Highways became a new company, spun out from TTP, with a seed fund to commercialise VACS in single-stream and parallel stream products

2019

2021

Alpha testing of Highway1 begins – we tested with 4 partners covering cell therapy, research, single-cell multi’omics, and liquid biopsy diagnostics

2021

2022

Cellular Highways completed a set of Highway1 beta prototypes, and tested at 16 beta sites

2022

2023

Cellular Highways launches Highway1 for research use, with GMP coming soon

2023
Our parent company, TTP plc

Our parent company, TTP plc

TTP is an independent technology company where scientists and engineers collaborate to invent, design and develop new products and technologies. Working across a wide spectrum of industries including health, telecoms, industrials and consumer, TTP creates breakthrough solutions that bring strong commercial value to clients and the benefits of technology to all.

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