Cell & Gene Therapy

High-performance GMP cell sorting

At Cellular Highways, we have built the fastest fluorescence-based cell isolation system for cell & gene therapy, to take you all the way from lab to production.

Highway1: Cell Sorting for Cell Therapy

The Highway1 Cell Sorting System is designed from the ground up for translation of cell and gene therapies. Our VACSTM technology makes it the fastest GMP ready cell sorter – 3.5x faster to your target cells than incumbent GMP multiparametric cell sorters.

Highway1 Cell Sorting System
  • Defined cell products GMP fluorescence-based sorting enables many applications including T cell therapy (CAR-T, TCR-T, Treg), stem cell therapy (iPSC, MSC, CD34) & more
  • Seamless translation Go all the way from R&D to GMP production with our GMP-ready technology, and the right version of the cartridge at each stage
  • Sterile Safeguard sterility with our sterile and fully-closed cartridges
  • Easy to use Fully automated and easy-to-use, reducing the burden on operators and freeing up capacity to focus on the things that matter
  • Lowering the cost of goods Access to life-transforming therapies shouldn’t be hindered by the cost of goods, our consumables are priced to remove these barriers
  • Backed by Quality Our products are manufactured in our cleanroom and under our QMS to give you confidence

GMP-ready cartridges

Use our high-performance sorting technology at every point of your journey. Highway1’s cartridges are designed with the right containers, validation and features for each stage: cell therapy research, process development, and manufacturing.

Highway1 GMP Pro Cartridges (Closed System): Fully Closed, Validated, Sterile Cell Sorting

4 Cartridge Types to Choose From:

  • GMP OS Cartridge (Open System) GMP validated but mechanically identical to the RUO cartridge, suitable for process development and small patient batches in high-grade cleanrooms
  • GMP Pro CS-B Cartridge (Closed System, Bag Output) Fully closed and GMP validated with output bags for downstream containment
  • GMP Pro CS-T Cartridge (Closed System, Tube Output) Fully closed and GMP validated with output tubes to weld straight onto the next process
  • RUO Cartridge Sterile and low-cost for research, process development, process controls and calibration, while being convenient for biology lab handling

Featured GMP Resources

See DFCI’s poster showing Highway1 performance against incumbent solutions:

Dana-Farber Cancer Institute – Selection of Specific T Cell Populations in clinical manufacturing of therapeutic cells (DFCI-poster-cell-sorting-for-process-development.pdf)

See our joint application note with Bio-Techne showing the applicability of their custom GMP antibodies on our platform:

GMP Treg Sorting with Highway1 and Bio-Techne Antibodies (GMP-sorting-with-Bio-Techne-GMP-antibodies-and-Highway1.pdf)

Click to watch our webinar: Highway1 for Cell Therapy:

The Highway1 is a giant step towards incorporating cell sorting in the manufacturing process of therapeutic cells.

— Dr Ruud Hulspas,
Technical Director of Process Development,
Dana Farber Cancer Institute